Your Cart

Zyncet Syrup 60Ml

Zyncet Syrup 60Ml - (007028) -
Zyncet Syrup 60Ml
Price per unit
  • Stock: 104
  • Model: Zyncet Syrup 60Ml
  • Pack Size: 1
  • SKU: 007028
  • Pack size: 1
  • Generic name: Cetrizine

COMPOSITION Each 5 ml contains Cetirizine Hydrochloride BP 5 mg. Excipients Propyl Hydroxy Benzoate, Methyl Hydroxy Benzoate, Sodium Acetate Anhydrous, Acetic Acid Glacial, Glycerin, Sucrose, Essence Banana (bush) & Purified Water. 

DESCRIPITION: Cetirizine is a potent antihistamine with a low potential for drowsiness at pharmacologically active doses and with additional anti-allergic properties. It is a selective H1- antagonist with negligible effects on the other receptors and so is virtually free from anti-cholinergic and anti-serotonin effects. Cetirizine inhibits the histamine mediatedearly' phase of allergic reaction and reduces the migration of inflammatory cells such as eosinophils and the release of mediators associated with the 'late' allergic response.

PHARMACOKINETICS: Peak blood levels of the order of 0.3 mcg/ml are reached between 30 to 60 minutes after oral administration of a 10 mg dose of Cetirizine. Its plasma half-life is approximately 1 1 hours. Absorption is very consistent from one subject to the next. Its renal clearance is 30ml/min, and the excretion half-life are approximately nine hours. Cetirizine is strongly bound to plasma proteins. 

INDICATIONS: Cetirizine is indicated for the symptomatic treatment of seasonal allergic rhinitis and perennial allergic rhinitis, allergic conjunctivitis, pruritis and urticaria. 

CONTRAINDICATIONS: Cetirizine syrup is contraindicated in patients with a history of hypersensitivity to any of the constituents. Cetirizine is contraindicated in lactating women since the active ingredient is excreted in breastmilk.  

PRECAUTIONS: Studies in healthy volunteers on 20 and 25 mg/day dose of Cetirizine have not revealed effects on alertness or reaction time. However, patients are advised not to exceed the recommended dose if driving or operating machinery. 

PREGNANCY: No adverse effects have been reported from animal studies. There has been little or no use of Cetirizine in pregnancy. As with other drugs, the use of Cetirizine in pregnancy should be avoided. 

DRUG INTERACTIONS: To date there are no known interactions with other drugs. Studies with Diazepam and Cimetidine have revealed no evidence of interactions. As with other antihistamines, it is advisable to avoid excessive alcohol consumption. 

ADVERSE EFFECTS: There have been occasional reports of mild and transient subjective adverse effects such as headache, dizziness, drowsiness, agitation, dry mouth and gastro-intestinal discomfort. If desired the dose may be taken as 5 mg in the morning and 5 mg in the evening. In objective tests of psychomotor function, the incidence of sedation with Cetirizine was similar to that of placebo. Occasionally symptoms of hypersensitivity have been reported. 

OVERDOSAGE: Drowsiness can be a symptom of overdosage, occurring from administration of 50 mg of Cetirizine as a single dose. the case of massive overdosage, gastric lavage should be performed together with usual supportive measures. To date there is no specific antidote. 

Manufactured in India by: The Madras Pharmaceuticals 


Write a review

Note: HTML is not translated!
Bad Good