Adiflam Sr 100Mg
- Stock: 1272
- Model: Adiflam Sr 100Mg
- Pack Size: 100
- SKU: 008225
- Pack size: 100
- Generic name: Diclofenac Sodium
DESCRIPTION Diclofenac a very commonly used non-steroidal anti-inflammatory drug, has analgesic, anti-pyretic actions. Diclofenac provides a novel NSAID for quick relief from pain, swelling inflammation, Adiflam is a brand name which stands for “Against the Flammation”. Adiflam-SR tablet is specially formulated to release the Diclofenac Sodium slowly. Adiflam Gel: Topical product for joints & muscular pain, anti-inflammatory preparations.
CLINICAL PHARMACOLOGY: Pharmacotherapeutic group: non-steroidal anti-inflammatory drugs (NSAlDs): It is an inhibitor of prostaglandin synthetase, (cyclo-oxygenase). Diclofenac sodium in vitro does not suppress proteoglycan biosynthesis in cartilage at concentrations equivalent to the concentrations reached in human beings.
INDICATIONS: Adiflam/Adiflam SR Tablet (Diclofenac Sodium): is indicated for rheumatoid arthritis, osteoarthritis, Low back pain, ankylosing spondylitis, gout, acute musculoskeletal disorders, periarthritis (frozen shoulder), tendinitis, tenosynovitis, bursitis, sprains, dislocations, painful post-operative conditions, pain following dental surgery & painful inflammatory conditions in gynecology. Adiflam Gel (Diclofenac Dimethylamine): This topical analgesic is indicated for the temporary relief of minor aches and pains of muscles and joints due to muscle strains, sprains and bruise or over exertion, as an adjunct in the management of minor stiffness or sourness associated with arthritis, rheumatism, lumbago, fibrositis, sciatica and stiff neck.
CONTRA INDICATIONS: Adiflam/Adiflam-SR Tablet/Adiflam Gel is contra- indicated in patients with known hypersensitivity to Diclofenac Sodium & Diclofenac Dimethylamine or to NSAID or in patients with severe or active peptic ulceration
DRUG INTERACTION: ACE Inhibitors: Increased risk of renal impairment when NSAlDs given with ACE inhibitors, also hypotensive effect antagonized. Adrenergic Neuron Blockers: NSAlDs antagonize hypotensive effect of adrenergic neuron blocker. Beta Blockers: NSAIDs antagonize hypotensive effect of Beta blocker. Cardiac Glycosides: NSAIDs possibly increase the plasma concentration of cardiac glycosides, also possible exacerbation of heart failure and reduction of renal function. Diuretics: Risk of nephrotoxicity of NSAlDs increased by diuretics.
SIDE EFFECT: Gastro-intestinal disturbances including discomfort, nausea, diarrhea, and occasionally bleeding and ulceration occur. Systemic as well as local effects of NSAIDs contribute to gastro-intestinal damage, taking oral formulation with milk or food or using enteric coated formulation or changing the route of administration may only partially reduce symptoms such as dyspepsia.
LEBEN LABORATORIES (PVT) LTD
