Alrin 180Mg

COMPOSITION

Alrin Tablet 60 mg: Each film coated tablet contains: Fexofenadine HCI USP 60 mg. Product Specs: USP. Alrin Tablet 120 mg: Each film coated tablet contains: Fexofenadine HCI USP 120 mg. Product Specs: USP. Alrin Tablet 180 mg: Each film coated tablet contains: Fexofenadine HCI USP 180 mg. Product Specs: USP.

DESCRIPTION

Fexofenadine Hydrochloride, the active ingredient of Alrin. is a non-sedating histamine H1 -receptor antagonist intended for oral administration.

INDICATIONS

Seasonal allergic rhinitis: Alrin is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 6 years of age and older Symptoms treated effectively were sneezing, rhinorrhea, itchy nose/palate/throat. itchy/watery/red eyes. Chronic idiopathic urticaria: Alrin is indicated for treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 years of age and older. It significantly reduces pruritus and the number of wheals.

CONTRAINDICATIONS

Alrin is contraindicated in patients with known hypersensitivity to any of its ingredients.

SIDE EFFECTS

In 4, 2-week. Placebo controlled seasonal allergic rhinitis trials with doses of 20 to 240 mL twice daily, adverse events were similar in Fexofenadine and placebo-treated patients. There was no dose-related increase in adverse events. including drowsiness. when administered up to 4 times the recommended therapeutic dose. Adverse event rates were similar among subgroups defined by age, gender and race. The rate of premature withdrawal because of adverse events was 2% (48/2346) with Fexofenadine vs 3.2% (22/685) with placebo.

OVERDOSAGE: Symptoms: Most reports of Fexofenadine overdose have been infrequent and contain limited information. The maximum tolerated dose of Fexofenadine was not established. Overall, there was no evidence of OTC prolongation at doses 11 times the recommended therapeutic dose. Treatment: In the event of overdose, standard measures to remove any unabsorbed drug should be Considered. Symptomatic and supportive treatment is recommended. Hemodialysis did not effectively remove Fexofenadine from blood (up to 1.7% removed) following terfenadine administration.

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