Amlong 5Mg
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Amlong 5Mg
- Stock: 717
- Model: Amlong 5Mg
- Pack Size: 100
- SKU: 004164
- Pack size: 100
- Generic name: Amlodipine
COMPOSITION
Each uncoated tablet contains Amlodipine Besylate USP equivalent to Amlodipine 5 mg.
INDICATIONS
Treatment of Prophylaxis of angina and Hypertension.
CONTRAINDICATIONS
Cardiogenic shock; significant aortic stenosis; unstable angina.
SIDE EFFECTS/ADVERSE EFFECTS
Common or very common: Abdominal pain; dizziness; fatigue; flushing; headache; nausea; oedema; palpitation; sleep disturbances. Uncommon: Alopecia; arthralgia; asthenia; back pain; chest pain; dry mouth; dyspnea; gastro-intestinal disturbances; gynecomastia; hypotension; impotence; mood changes; muscle cramps; myalgia; paresthesia; pruritus; purpura; rashes; rhinitis; skin discoloration; sweating; syncope; taste disturbances; tinnitus; tremor; urinary disturbances; visual disturbances; weight changes. Very rare: Angioedema; arrhythmias; cholestasis; coughing; gastritis; gingival hyperplasia; hepatitis; hyperglycemia; jaundice; myocardial infarction; pancreatitis; peripheral neuropathy; tachycardia; thrombocytopenia; urticaria; vacuities.
PRECAUTIONS & WARNINGS
Patients with cardiac failure: Patients with heart failure should be treated with caution. In a long-term, placebo-controlled study in patients with severe heart failure (NYHA class Ill and IV) the reported incidence of pulmonary oedema was higher in the amlodipine treated group than in the placebo group. Calcium channel blockers, including amlodipine, should be used with caution in patients with congestive heart failure, as they may increase the risk of future cardiovascular events and mortality. Use in patients with impaired hepatic function: The half-life of amlodipine is prolonged and AUC values are higher in patients with impaired liver function; dosage recommendations have not been established. Amlodipine should therefore be initiated at the lower end of the dosing range and caution should be used, both on initial treatment and when increasing the dose. Slow dose titration and careful monitoring may be required in patients with severe hepatic impairment. Use in elderly patients: In the elderly increase of the dosage should take place with care.
OVERDOSAGE & TREATMENT: In humans experience with intentional overdose is limited Symptoms: Available data suggest that gross over dosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to and including shock with fatal outcome have been reported. Treatment: Clinically significant hypotension due to amlodipine over dosage calls for active cardiovascular support including frequent monitoring of cardiac and respiratory function, elevation of extremities and attention to circulating fluid volume and urine output. A vasoconstrictor may be helpful in restoring vascular tone and blood pressure, provided that there is no contraindication to its use. Intravenous calcium gluconate may be beneficial in reversing the effects of calcium channel blockade Gastric lavage may be worthwhile in some cases. In healthy volunteers the use of charcoal up to 2 hours after administration of amlodipine 10 mg has been shown to reduce the absorption rate of amlodipine. Since amlodipine is highly protein-bound, dialysis is not likely to be of benefit.
MICRO LABS LIMITED
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