Anemidox

COMPOSITION

Each hard gelatin capsule contains: Ferrous Fumarate USP 360 mg. Folic Acid USP 400 mcg. Cyanocobalamin Triturate in Gelatin equivalent to Cyanocobalamin USP 15 mcg. Calcium Carbonate USP 200 mg. Cholecalciferol USP 400 IU. Ascorbic Acid coated equivalent to Ascorbic Acid USP 75 mg. Colours used in capsule shell: Tartrazine, Brilliant Blue FCF, Erythrosine, Titanium Dioxide USP. Preservatives used in capsule shell: Methylparaben USP-NF, Propylparaben USP-NF or its salt derivatives “for therapeutic use”. 

INDICATIONS

Anemidox capsule is indicated for: Treatment or prophylaxis of iron deficiency anemia. Use as diet supplement especially for women of child bearing age and in physiological states like pregnancy. Therapy of pernicious and megaloblastic anemias. 

CONTRAINDICATIONS

Hemochromatosis, hemosiderosis, hemolytic anemias: Hypercalemia, ventricular fibrillation: malabsorption syndrome; hypervitaminosis D; decreased renal function. Previous intolerance or hypersensitivity to any ingredient of the formulation. 

WARNINGS

Individuals with normal iron balance should not take iron chronically. Accidental overdosage of iron-containing products is a leading cause of fatal poisoning in children younger than 6 yean of age. 

PRECAUTIONS

Discontinue use if symptoms of intolerance appear. Diabetic patients, patients prone to recurrent renal calculi, those undergoing stool occult blood tests and those on sodium restricted diets or anticoagulant therapy should not take excessive doses of vitamin C over an extended period of time. Give to pregnant women only if absolutely needed. Avoid concurrent aluminum containing antacids. Administer with caution to nursing mothers. 

DRUG INTERACTIONS

Absorption of cyanocobalamin, from the gastrointestinal tract may be reduced by neomycin, aminosalicylic acid, histamine H2 antagonists and colchicine’s. Serum concentrations may be decreased by concurrent use of oral contraceptives. Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia. Folic acid supplementation has reportedly decreased serum-phenytoin concentrations in few cases. Large doses (greater than 500 mg) of vitamin C may cause false-negative urine glucose determination. 

OVERDOSAGE

In acute overdosage zinc salts are corrosive, due to formation of zinc chloride by stomach acid; treatment consists of giving milk or alkali carbonates and activated charcoal. The use of emetics or gastric lavage should be avoided. High serum zinc concentrations may be reduced by using a chelating agent like sodium calcium edetate. Overdosage of selenium has been associated with loss of hair, nail changes, diarrhoea, dermatitis, metallic taste, garlic odour of breath, irritability, fatigue and peripheral neuropathy. 

Procter & Gamble Health Ltd