Celenta 100Mg

CONTRAINDICATIONS

Celecoxib is contraindication in patients with active GI bleeding, active ulcer, cerebrovascular disease. inflammatory bowel disease, ischemic heart disease, mild to severe heart failure, peripheral arterial disease, asthma, urticaria, in patients with known hypersensitivity to celecoxib and sulfonamides and in patients who have shown allergic reaction after taking aspirin or other NSAlDs. 

PRECAUTIONS

Celecoxib should be used with caution in patient with caution in patient with allergic disorder, cardiac impairment. coagulation defects, connective tissue disorders, Crohn's disease, hypertension, left ventricular dysfunction, oedema, risk factors for cardiovascular events, ulcerative colitis etc. Blood pressure should be monitored before and during treatment. Celecoxib cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids. Celecoxib should be prescribed with extreme caution in patients with a prior history of G.I. ulcer-disease or G.I. bleeding, hepatic and renal insufficiency, heart failure. those taking diuretics and ACE inhibitors, pre-existing asthma, elderly patients.

SIDE EFFECTS

Common and very common side effects include dyspnea, influenza like symptoms. Uncommon side effects include cerebral infarction, fatigue, muscle cramps, palpitation, paresthesia, stomatitis. Rare side effects include alopecia, alveolitis, aseptic meningitis (patients with connective tissue disorder such as systemic lupus erythematosus may be especially susceptible), hepatic damage. interstitial fibrosis associated with NSAlDs can lead to renal failure, pancreatitis, papillary necrosis, pulmonary eosinophilia, Stevens-Johnson syndrome, taste disturbance, toxic epidermal necrolysis, visual disturbances. Very rare side effect is seizures.