Montene 10Mg

COMPOSITION

Montene 4 Tablet Each orodispersible tablet contains Montelukast Sodium EP equivalent to Montelukast 4 mg. Montene 5 Tablet Each orodispersible tablet contains Montelukast Sodium EP equivalent to Montelukast 5 mg. Montene 10 Tablet Each film-coated tablet contains Montelukast Sodium EP equivalent to Montelukast 10 mg. 

INDICATION

Montelukast is a leukotriene receptor antagonist indicated for: Prophylaxis and chronic treatment of asthma in patients 12 months of age and older. Acute prevention of Exercise-induced Bronchoconstriction (EIB) in patients 6 years of age and older. Relief of symptoms of Allergic Rhinitis (AR): Seasonal Allergic rhinitis (SAR) in patients 2 years of age and older, and perennial allergic rhinitis (PAR) in patients 6 months of age and older. 

CONTRAINDICATION

Hypersensitivity to any component of this product. 

ADVERSE EFFECT

Montelukast appears to be well tolerated. In clinical trials, the most common adverse effect reported was headache, occurring in approximately 18% of patients. Rash, dyspepsia, dizziness, and abdominal pain were all reported in less than 2% of patients. Elevated liver transaminases have been reported with montelukast use, but not at a greater incidence than with placebo. A small percentage of pediatric patients have experienced diarrhea, sinusitis and otitis media during montelukast clinical trials. 

PRECAUTION

Montelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks, including status asthmaticus. Patients should be advised to have appropriate rescue medication available.  

DRUG INTERACTION

Montelukast may be administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma. In drug-interactions studies, the recommended clinical dose of montelukast did not have clinically important effects on the following medicinal products: theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin and warfarin. Caution should be exercised, particularly in children, when montelukast is co-administered with phenytoin, phenobarbital and rifampicin. 

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